Abdelfattah Faouzi - PhD student

Highly self-motivated PhD student with demonstrated research expertise in organic chemistry and analytical techniques. Strong interpersonal skills emphasized by fluency in English, very good command in both spoken and written Spanish, and native speaker of French and Arabic.

Education

2014 – present:  PhD Candidate in Medicinal Chemistry with teaching duty.

- EA4446 Biomolecules, Cancer and Chemoresistances (B2C), Department of Medicinal Chemistry, University of Claude Bernard Lyon 1, Lyon. "Synthetic approaches and biological evaluations of Combretastatin A-4 derivatives and Dyrk kinase inhibitors". Supervisors : Pr. Marc Le Borgne and Pr. Thierry Lomberget.

2012 – 2014: Master of Science

- Biological and Pharmaceutical Sciences Institute (ISPB), University of Claude Bernard Lyon 1, Lyon. Master Degree in Drug Sciences: Analytical Development and Biopharmaceutics. Magna Cum Laude.

2010 – 2012: Bachelor of Science

- University of Claude Bernard Lyon 1, Lyon. Bachelor Degree in Biochemistry.

Work Experience

August 2015 – March 2016: Teaching Experience

Institut Premium, 114 cours Albert Thomas, 69008 Lyon. Organic chemistry courses: 1st year Pharmacy and Medicine student.

January 2014 – July 2014: Research trainee

EA4446 Biomolecules, Cancer and Chemoresistances (B2C), Department of Medicinal Chemistry, University of Claude Bernard Lyon 1, Lyon. Title : "Synthetic Approaches and Biological Evaluation of Combretastatin A-4 derivatives".

May 2013 – June 2013: Research trainee

EA4446 Biomolecules, Cancer and Chemoresistances (B2C), Department of Medicinal Chemistry, University of Claude Bernard Lyon 1, Lyon. Title: "Benzo[b]thiophene derivatives synthesis as Combretastatin A-4 analogs".

Research

Refereed Journal Articles

Abdelfattah Faouzi, Cong Viet Do, Caroline Barette, Amaury Farce, Marie-Odile Fauvarque, Evelyne Colomb, Laura Catry, Odile Berthier-Vergnes, Marek Haftek, Roland Barret and Thierry Lomberget. Synthesis and biological evaluation of 
thiophene and benzo[b]thiophene analogs 
of combretastatin A-4 and isocombretastatin
A-4: a comparison between the linkage 
positions of the 3,4,5-trimethoxystyrene unit. Bioorganic and Medicinal Chemistry Letters, 2016, 26 (1), 174-180.

Communications 

Abdelfattah Faouzi, Thierry Lomberget, Cong Viet Do, Caroline Barrette, Thi Thanh Binh Nguyen, Marie-Odile Fauvarque, Evelyne Colomb, Marek Haftek and Roland Barret. "Synthetic approaches and biological evaluation of combretastatin A-4 derivatives: new cis and iso microtubule polymerization inhibitor." Presented in Science Day of EDISS, Lyon 1 University, October 2015.
Abdelfattah Faouzi, Thierry Lomberget, Cong Viet Do, Caroline Barrette, Thi Thanh Binh Nguyen, Marie-Odile Fauvarque, Evelyne Colomb, Marek Haftek and Roland Barret. "Synthetic approaches and biological evaluation of combretastatin A-4 derivatives: new cis and iso sulfur containing analogs". Presented in TTMC 2015, Münster PharmaCampus, August 2015.
Abdelfattah Faouzi, Caroline Barette, Marie-Odile Fauvarque, Evelyne Colomb, Marek Haftek, Rolland Barret and Thierry Lomberget."Synthetic approaches and biological evaluation of novel combretastatin A-4 derivatives as potent microtubule polymerization inhibitors". Presented in the Vth day of Biomolecules in Rhône-Alpes (JRAB), "Biomolecules: from the identification to the use as tools for the diagnosis, targeting and therapy", Analytical Sciences Institute (ISA), 5 rue de la Doua, Villeurbanne, June 2016.

Honors and Awards

2nd Poster Prize Winner

Abdelfattah Faouzi, Caroline Barette, Marie-Odile Fauvarque, Evelyne Colomb, Marek Haftek, Rolland Barret and Thierry Lomberget. "Synthetic approaches and biological evaluation of novel combretastatin A-4 derivatives as potent microtubule polymerization inhibitors". Vth day of Biomolecules in Rhône-Alpes (JRAB), "Biomolecules: from the identification to the use as tools for the diagnosis, targeting and therapy", Analytical Sciences Institute (ISA), 5 rue de la Doua, Villeurbanne, June 2016.

Additional Information and Interests

English certificate TOEIC C2 level (945/990)

Experimental techniques: Organic synthesis, Structure Activity Relationship (SAR), NMR, Mass spectrometry, HPLC.
Teaching experience: Postgraduate courses taught (1st year Bachelor student, 3rd and 4th year Pharmacy students): English and Medicinal Chemistry.
Computer Skills: Chemistry software (ChemDraw, Chemsketch, Mestre-C, NMRnotebook), Microsoft Office (Powerpoint, Word, Excel), Scientific literature applications (Scifinder, Reaxys, Pubmed, Science Direct).

Sport: CrossFit (CrossFit Lyon), Football practice for 8 years (Captain of U.S JASSANS team), Running (marathon "Run in Lyon 2014")
Travelling: Canada (February and May 2014), Morocco, Spain, Malta and Switzerland.